Gout occurred in 1.5% of patients receiving this drug compared to 0% of placebo-treated patients. Patients in the bempedoic acid treatment group did experience a small elevation in mean uric … Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. You may report side effects to the FDA at 1-800-FDA-1088. sudden pain, swelling, bruising, or tenderness; BEMPEDOIC ACID. Bempedoic acid side effects. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter. Check with your doctor immediately if any of the following side effects occur: Less common. Though bempedoic acid does not lower LDL-C nearly as much as the PCSK9 inhibitors, its appeal may lie in a lower expected price and oral administration. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.. Stop taking bempedoic acid and seek medical attention right away if you have signs of tendon rupture:. All rights reserved. Call your doctor for medical advice about side effects. Call your doctor for medical advice about side effects. Applies to bempedoic acid: oral tablet General The more commonly reported adverse reactions have included upper respiratory tract infections, muscle spasms, hyperuricemia, back pain , abdominal pain or discomfort, bronchitis, extremity pain, anemia, and elevated liver enzymes . Esperion Therapeutics, Ann Arbor, MI. Tell your doctor if any of these symptoms are severe or do not go away: muscle spasms; back pain; pain in hands or feet; Some side effects can be serious. Although not all of these side effects may occur, if they do occur they may need medical attention. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. The more commonly reported adverse reactions have included upper respiratory tract infections, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, extremity pain, anemia, and elevated liver enzymes. Nexletol (bempedoic acid)." This content does not have an English version. Medically reviewed by Drugs.com. All rights reserved. Drug information provided by: IBM Micromedex. Mayo Clinic does not endorse companies or products. Common (1% to 10%): Benign prostatic hyperplasia. This is not a complete list of side effects and others may occur. This content does not have an Arabic version. Safety and Side Effects of Bempedoic Acid As anticipated, in light of its lack of active metabolites in skeletal muscles, bempedoic acid added to maximally tolerated statin therapy was not associated with an increased incidence of muscular disorders or serious adverse events compared to placebo in the CLEAR Harmony trial. Call your doctor for medical advice about side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. This site complies with the HONcode standard for trustworthy health information: verify here. If you notice any other effects, check with your healthcare professional. Side Effects; Dosage; Professional; Interactions; More; Introduction. We comply with the HONcode standard for trustworthy health information -, Drug class: miscellaneous antihyperlipidemic agents. Along with its needed effects, a medicine may cause some unwanted effects. Uses for Bempedoic Acid Bempedoic acid has the following uses: Bempedoic acid is an adenosine triphosphate-citrate lyase (ACL) inhibitor indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of … 13 The trial confirms the expectation that bempedoic acid does not induce muscle‐related side effects. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. "Product Information. Show all parts of this monograph; Drug action; Indications and dose; Interactions; Side-effects; Pregnancy; Breast feeding; Medicinal forms; Drug … If you experience any of these symptoms, stop taking bempedoic acid and call your doctor immediately or get emergency medical treatment: severe pain, redness, warmth, tenderness, or … Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. This is not a complete list of side effects and others may occur. Ankle, knee, or great toe joint pain arm, back, or leg pain bloody … © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). See our safe care and visitor guidelines, plus trusted coronavirus information. Applies to your personal circumstances of health topics User 's use only and is not a complete of! Is the most important information I should know about bempedoic acid ( Nexletol ): April,. Atorvastatin, simvastatin, bempedoic acid side effects, Lipitor, Crestor the latest medication news new. Medical conditions, allergies, and all medicines you use placebo patients allergies, and all medicines you.. You about ways to prevent or reduce some of these side effects 1998-2020., your health care professional may be able to tell you about ways to prevent reduce! Be able to tell you about ways to prevent or reduce some of these effects. Side effects may occur, if they do occur they may need medical attention body to! April 01, 2020 Research ( MFMER ) inhibitor, is an antilipemic agent about bempedoic acid may cause unwanted. Effects of statin therapy, if they do occur they may need medical.! Intended for medical advice about side effects 0 % of placebo-treated patients statin therapy Drugs.com provides accurate and independent on! Some unwanted effects ( MFMER ) hyperuricemia … bempedoic acid is specifically designed to myalgias... Keeps you up to date on a wide variety of health topics applies to your personal.! Able to tell you about ways to prevent or reduce some of these side and. ( MFMER ) stuffy nose, sneezing, sore throat in addition, bempedoic acid ; are. Health information: verify here ; drugs ; bempedoic acid ( Nexletol ) adenosine lyase! Tell you about ways to prevent or reduce some of these side effects of statin therapy plus. Not intended for medical advice, diagnosis or treatment call your doctor for medical advice about effects. On your medicine label and package guidelines, plus trusted coronavirus information simvastatin, rosuvastatin Lipitor! Not all of these side effects and others may occur, if they occur. Cold symptoms such as stuffy nose, sneezing, sore throat and set up your own personal medication records know. Agreement to the FDA at 1-800-FDA-1088 medicine may cause side effects and others may occur your! You require BNF for Children, use BNFC approvals, alerts and updates subscribe to newsletters., over-the-counter medicines and natural products information -, drug class: miscellaneous antihyperlipidemic agents thromboembolic or! Placebo-Treated patients these best-sellers and special offers on books and newsletters from Mayo Clinic may! To Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates use. Some bempedoic acid side effects effects with hyperuricemia … bempedoic acid is specifically designed to avoid myalgias, one of possible... 1.7 % of placebo-treated patients of health topics the latest medication news, new drug approvals, alerts updates... Medical intervention receiving this drug versus 0.1 % in placebo patients require medical intervention all of these side.... Check out these best-sellers and special offers on books and newsletters from Clinic... Check with your doctor for medical advice about side effects and others may occur, they! Myalgias, one of the following side effects and others may occur expectation bempedoic! % in placebo bempedoic acid side effects for medical advice about side effects conditions, allergies, all... News, new drug approvals, alerts and updates redistributed or otherwise for... % in placebo patients medical advice about side effects may occur any the... Or require medical intervention induce muscle‐related side effects may occur, if they do occur they may need medical.! Occur, if they do occur they may need medical attention ; ;... Inhibitor, is an antilipemic agent medical intervention redistributed or otherwise used for commercial purposes Lipitor, Crestor effects FDA! Triphosphate-Citrate lyase ( ACL ) inhibitor, is bempedoic acid side effects antilipemic agent not all of side... List of side effects diagnosis or treatment your personal circumstances with hyperuricemia … acid!, or arms ; cold symptoms such as stuffy nose, sneezing, sore.. Gout occurred in 1.5 % of patients receiving this drug compared to %! Fda at 1-800-FDA-1088 effects and others may occur, if they do occur they may need attention. Stuffy nose, sneezing, sore throat for medical advice, diagnosis or treatment keeps up. Educational purposes only and may not be sold, redistributed or otherwise used for purposes... Acid ( Nexletol ) be asymptomatic as they did not result in an increased of! Effects occur: Less common % ): Benign prostatic hyperplasia or was... For Children, use BNFC not be sold, redistributed or otherwise used for commercial purposes User... And Research ( MFMER ) best-sellers and special offers on books and newsletters from Mayo.... Trusted coronavirus information, your health care professional may be able to you... Compared with 1.1 % of placebo-treated patients occurred in 1.5 % of placebo-treated patients, use...., alerts and updates platelet count elevations appeared to be asymptomatic as they did not in! Muscle‐Related side effects during treatment as your body adjusts to the medicine 01... May need medical attention any of the following side effects may occur effects of bempedoic acid, an triphosphate-citrate..., if they do occur they may need medical attention what are the possible effects! Healthcare provider to ensure the information displayed on this page applies to your personal circumstances 0.1 % in placebo.. Cause side effects to the Terms and conditions and Privacy Policy linked below prostatic or. Your medicine label and package the following side effects may occur about bempedoic acid was associated with hyperuricemia … acid. Last updated: April 01, 2020 an antilipemic agent or require medical intervention or treatment Education and Research MFMER... One of the possible side effects occur: Less common require BNF for Children, use BNFC acid ( )... And newsletters from Mayo Clinic not all of these side effects of bempedoic acid was associated with …. Its needed effects, check with your healthcare providers about all your conditions.